Clinical relevance of Mycoplasma pneumoniae macrolide resistance in children.
نویسندگان
چکیده
Fabio Cardinale, Maria Chironna, Iolanda Chinellato, Nicola Principi, Susanna Esposito Department of Pediatric Allergy and Pulmonology, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy; Hygiene Section, Department of Biomedical Sciences and Human Oncology, Azienda Ospedaliero-Universitaria Policlinico, University of Bari, Bari, Italy; Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
منابع مشابه
Prevalence of mycoplasma pneumoniae and macrolide resistance in children with community-acquired pneumonia: a case study in a teaching hospital
Background: Mycoplasma pneumoniae is one of the causes of upper and lower respiratory tract infections especially in children, and antibiotics affecting the cell wall do not affect this type of infection. This study aimed to evaluate the prevalence of Mycoplasma pneumoniae and macrolide resistance in children with community-acquired pneumonia in Kerman city. Methods: This cross-sectional study...
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Mycoplasma pneumoniae is the major pathogen of community-acquired pneumonia in children. The prevalence of macrolide-resistant M. pneumoniae (MRMP) is important owing to the limited alternative therapies for children. We analyzed 111 M. pneumoniae obtained from 107 children admitted for lower respiratory tract infection at Jeju National University Hospital between 2010 and 2015. Macrolide resis...
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PURPOSE Macrolide resistance rate of Mycoplasma pneumoniae has rapidly increased in children. Studies on the clinical features between macrolide susceptible-M. pneumoniae (MSMP) and macrolide resistant-M. pneumoniae (MRMP) are lacking. The aim of this study was to identify the macrolide resistance rate of M. pneumoniae in Korean children with M. pneumoniae penupmonia in 2015 and compare manifes...
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OBJECTIVES Mycoplasma pneumoniae is a frequent cause of human lower respiratory tract infections (LRTIs) for which macrolides are the treatment of choice. The aim of this study was to determine the rate of macrolide resistance and to subtype M. pneumoniae strains in Italy. PATIENTS AND METHODS During an outbreak of M. pneumoniae infections in southern Italy in 2010, 48 clinical specimens from...
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Fifty clinical Mycoplasma pneumoniae strains were isolated from 370 children with respiratory tract infections. Four strains were susceptible to macrolides, while the other 46 (92%) were macrolide resistant. The molecular mechanism of resistance was shown to be associated with point mutations in 23S rRNA at positions 2063 and 2064.
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 51 2 شماره
صفحات -
تاریخ انتشار 2013